Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 8/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648358 | 0.81 | CTSK (0.49) | SYKCTSKCTSSMEN1GAA | |
| SCHEMBL5158937 | 0.80 | SERPINE1 (0.40) | SERPINE1SYKCTSKCTSSAAK1 | |
| SCHEMBL9417108 | 0.78 | GAA (0.45) | SERPINE1SYKCTSKGAAATM | |
| SCHEMBL9536094 | 0.78 | SYK (0.39) | SERPINE1SYKCTSKCTSSAAK1 | |
| SCHEMBL6167126 | 0.77 | KDM4A (0.44) | SYKCTSKCTSSMEN1GAA | |
| SCHEMBL9938243 | 0.76 | CTSS (0.46) | SYKCTSKCTSSATM | |
| SCHEMBL3996179 | 0.74 | GAA (0.41) | CTSKGAA | |
| SCHEMBL16690906 | 0.73 | AAK1 (0.43) | SERPINE1SYKCTSKCTSSAAK1 | |
| SCHEMBL12791343 | 0.72 | GRM2 (0.46) | CTSKCTSSGAAKDM4A | |
| SCHEMBL23360845 | 0.72 | SERPINE1 (0.37) | SERPINE1SYKCTSKCTSSAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114158-A1 | 3-SUBSTITUTED-[1,2,3]BENZOTRIAZINONE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008085505-A1 | 3-SUBSTITUTED-[1,2,3]BENZOTRIAZINONE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | WO | disclosed |