Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | UBE2N | P61088 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534400 | 0.79 | PDE1A (0.51) | ADORA1MAPK1 | |
| SCHEMBL9536256 | 0.79 | TAS2R14 (0.45) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9039076 | 0.79 | TAS2R14 (0.48) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9039454 | 0.77 | TAS2R14 (0.46) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9972909 | 0.77 | LMNA (0.48) | TAS2R14ADORA2BPIK3CDPOLBADORA3 | |
| SCHEMBL9038372 | 0.77 | TAS2R14 (0.46) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9972893 | 0.77 | TAS2R14 (0.43) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9039797 | 0.76 | TAS2R14 (0.48) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9039947 | 0.73 | TAS2R14 (0.44) | TAS2R14UBE2NADORA2BPIK3CDPOLB | |
| SCHEMBL9538645 | 0.73 | TAS2R14 (0.46) | TAS2R14LMNAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0243311-B1 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4808587-A | ANTIALLEGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |