Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741223 | 0.73 | EPHX2 (0.48) | GAAEPHX2 | |
| SCHEMBL8741267 | 0.67 | PARP1 (0.42) | PPARGKMT2A | |
| SCHEMBL9530397 | 0.66 | BRS3 (0.40) | MMEAGTR1PPARG | |
| SCHEMBL7324034 | 0.65 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL9297390 | 0.65 | PPARG (0.61) | PPARGMEN1KMT2AEPHX2 | |
| SCHEMBL9333932 | 0.65 | AGTR1 (0.44) | AGTR1MEN1KMT2A | |
| SCHEMBL8954337 | 0.65 | EPHX2 (0.38) | KMT2AEPHX2 | |
| SCHEMBL9529061 | 0.64 | CYP1A2 (0.39) | MMEPPARG | |
| SCHEMBL9052148 | 0.63 | PARP1 (0.40) | PPARG | |
| SCHEMBL6703361 | 0.62 | PARP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561941-A1 | N-SUBSTITUTED LACTAMS USEFUL AS CHOLECYSTOKININ ANTAGONISTS. | SEARLE & CO (US) | 1993-09-29 | — | — | EP | disclosed |