Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.46 |
| ▸ | USP10 | Q14694 | 1/20 | 0.46 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536605 | 0.85 | USP7 (0.44) | USP7USP10USP47MAPTALDH1A1 | |
| SCHEMBL9538302 | 0.79 | ATM (0.50) | USP7USP10USP47MAPTMEN1 | |
| SCHEMBL9538068 | 0.78 | PTGS2 (0.39) | MAPTALDH1A1KDM4EPTGS2SLC6A4 | |
| SCHEMBL9655130 | 0.76 | HSPB1 (0.57) | MEN1KMT2AATMTDP1HSPB1 | |
| SCHEMBL9538133 | 0.74 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL2870229 | 0.72 | VCAM1 (0.44) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9535630 | 0.72 | USP7 (0.53) | USP7USP10USP47MAPTALDH1A1 | |
| SCHEMBL773066 | 0.72 | VCAM1 (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL1340757 | 0.72 | PDE7A (0.55) | USP7USP10USP47MAPTALDH1A1 | |
| SCHEMBL9535266 | 0.71 | MAPT (0.62) | USP7USP10USP47MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |