Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534354 | 0.87 | PTGS2 (0.54) | PTGS2PTGS1MOGAT2PGR | |
| SCHEMBL9535031 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1MOGAT2SLC22A12 | |
| SCHEMBL9656891 | 0.78 | PTGS2 (0.56) | PTGS2SLC22A12AR | |
| SCHEMBL9538068 | 0.76 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL9537442 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL9536162 | 0.74 | USP7 (0.46) | PTGS2PTGS1 | |
| SCHEMBL9535342 | 0.73 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL9537176 | 0.73 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL9536821 | 0.73 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL1013625 | 0.72 | KIF11 (0.43) | PTGS2PTGS1MOGAT2SLC22A12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |