Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532314 | 0.91 | LTB4R (0.41) | PPARGRARGRXRALTB4RLTB4R2 | |
| SCHEMBL9536665 | 0.91 | LTB4R (0.40) | PPARGRARGRXRALTB4RLTB4R2 | |
| SCHEMBL9535011 | 0.88 | PPARG (0.42) | PPARGRARGRXRALTB4RLTB4R2 | |
| SCHEMBL9121904 | 0.87 | MAPT (0.43) | PPARGRARGRXRALTA4HHRH3 | |
| SCHEMBL9123920 | 0.85 | LTB4R (0.46) | PPARGRARGRXRALTB4RLTB4R2 | |
| SCHEMBL9533468 | 0.83 | MEN1 (0.41) | ITGB3ITGA2BPPARGRARGRXRA | |
| SCHEMBL10468305 | 0.83 | NPY5R (0.44) | PPARGRARGRXRALTA4HHRH3 | |
| SCHEMBL9536496 | 0.82 | PPARG (0.61) | PPARGRARGRXRA | |
| SCHEMBL9325005 | 0.81 | PPARG (0.48) | PPARGRARGRXRALTA4HHRH3 | |
| SCHEMBL9326656 | 0.79 | HRH3 (0.48) | PPARGHRH3MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |