Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536565 | 0.79 | PDE7A (0.54) | MAPTPOLBL3MBTL1PDE7AKMT2A | |
| SCHEMBL9535213 | 0.78 | PTGS2 (0.56) | MAPTPOLBPRKCIKMT2AMEN1 | |
| SCHEMBL9537872 | 0.76 | HPGD (0.59) | MAPTPOLBL3MBTL1PDE7APRKCI | |
| SCHEMBL2785747 | 0.75 | HPGD (0.60) | MAPTPOLBL3MBTL1KMT2AMEN1 | |
| SCHEMBL9535794 | 0.75 | CREBBP (0.40) | MAPTPOLBL3MBTL1PDE7APRKCI | |
| SCHEMBL9535335 | 0.72 | MAPT (0.53) | MAPTPOLBL3MBTL1PDE7APRKCI | |
| SCHEMBL9535529 | 0.72 | MAPT (0.43) | MAPTPOLBL3MBTL1PDE7APRKCI | |
| SCHEMBL27274014 | 0.71 | FBP1 (0.39) | MAPTPOLBL3MBTL1PDE7AKMT2A | |
| SCHEMBL9539495 | 0.71 | PDE7A (0.39) | MAPTPOLBPDE7AKMT2AMEN1 | |
| SCHEMBL9536561 | 0.71 | MAPT (0.57) | MAPTPOLBL3MBTL1PDE7APRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |