SCHEMBL953683

SCHEMBL953683

[NH]C(=O)COc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.68
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
FFAR1 O14842 1/20 0.50
GAA P10253 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
AOC3 Q16853 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
PTPN7 P35236 1/20 0.48
PTPN12 Q05209 1/20 0.48
MAOB P27338 1/20 0.48
PKM P14618 1/20 0.48
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3898377 0.81 ALOX15 (0.74) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL1318870 0.81 ALOX15 (1.00) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL8127 0.81 ALOX15 (1.00) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL10968825 0.80 LTA4H (0.45) ALOX15RAB9AMAPTLMNA
Hydrochloric Acid SCHEMBL7049631 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL11853257 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL9243904 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL2168445 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI
Ammonia Solution, Strong SCHEMBL6844286 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI
Methane SCHEMBL7339930 0.79 ALOX15 (0.95) ALOX15KMT2AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118127115-A Method for preparing phenoxyacetamido penicillin potassium salt through two-step catalysis 内蒙古常盛制药有限公司 2024-06-04 CN claimed
CN-117946031-A Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors 北京大学 2024-04-30 CN claimed
CN-117106844-A Method for synthesizing phenoxyacetamido penicillin potassium salt by fermentation method 内蒙古常盛制药有限公司 2023-11-24 CN claimed
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US claimed
CN-116589482-A Metal beta-lactamase fluorescent probe and preparation method and application thereof 南京工业大学 2023-08-15 CN claimed
EP-4182325-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND Aarhus Universitet (DK) 2023-05-24 EP claimed
CN-111718361-B Metal beta-lactamase inhibitor and preparation method and application thereof 南京工业大学 2022-04-05 CN claimed
WO-2022013393-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2022-01-20 WO claimed
CN-111718361-A Metal beta-lactamase inhibitor and preparation method and application thereof 南京工业大学 2020-09-29 CN claimed
EP-1831198-B1 PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS ASTRAZENECA AB (SE) 2009-04-08 EP claimed
US-4046757-A 2-Optionally substituted alkyl-and phenylsulfonylphenyl-azo-phenyl dyes and a process for their synthesis SANDOZ LTD. (CH) 1977-09-06 US claimed
US-4042585-A Process for preparation of 3-halomethylcephems ELI LILLY AND COMPANY (US) 1977-08-16 US claimed
US-4038275-A PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS ELI LILLY AND COMPANY (US) 1977-07-26 US claimed
US-4031084-A Process for cephalosporin antibiotic intermediates ELI LILLY AND COMPANY (US) 1977-06-21 US claimed
US-4022773-A 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, 1-OXIDES ISHIMARU TOSHIYASU 1977-05-10 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3989685-A FROM PENICILLIN-1-OXIDE SHINOGI & CO., LTD. (JA) 1976-11-02 US claimed
US-3978039-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-24 US claimed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US claimed
US-3951951-A Azetidinones BEECHAM GROUP LIMITED (EN) 1976-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND RNGTT, PPA1, PNP ALOX15 1654/4885KMT2A 1658/4885MEN1 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.