Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP7 | Q93009 | 2/20 | 0.49 |
| ▸ | USP10 | Q14694 | 1/20 | 0.49 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535630 | 0.80 | USP7 (0.53) | ATMTDP1USP7USP10USP47 | |
| SCHEMBL9538632 | 0.80 | G6PD (0.58) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL9538420 | 0.78 | USP7 (0.60) | ATMTDP1USP7USP10USP47 | |
| SCHEMBL1340757 | 0.77 | PDE7A (0.55) | ATMTDP1USP7USP10USP47 | |
| SCHEMBL28503304 | 0.77 | MAPT (0.56) | TDP1PDE7AALDH3A1KMT2AMEN1 | |
| SCHEMBL28387623 | 0.77 | HTT (0.60) | PDE7AALDH3A1KMT2AMEN1LMNA | |
| SCHEMBL9537312 | 0.76 | USP7 (0.52) | ATMTDP1USP7USP10USP47 | |
| SCHEMBL9538302 | 0.76 | ATM (0.50) | PTGS2ATMTDP1USP7USP10 | |
| SCHEMBL9537442 | 0.76 | PTGS2 (0.58) | PTGS2PTGS1LMNAPTGDR2 | |
| SCHEMBL9535526 | 0.75 | USP7 (0.51) | ATMTDP1USP7USP10USP47 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |