Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535585 | 0.84 | POLB (0.59) | KMT2AALDH1A1SNCAMAPTL3MBTL1 | |
| SCHEMBL3408482 | 0.74 | MAOB (0.46) | KMT2AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL31570085 | 0.72 | MAPT (0.64) | KMT2AALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL9536901 | 0.71 | HDAC1 (0.51) | ALDH1A1MAPTL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL20941598 | 0.71 | ALDH1A1 (0.62) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2556599 | 0.71 | MAPT (0.62) | KMT2AALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL4707612 | 0.71 | CES2 (0.59) | ALDH1A1SNCAMAPTL3MBTL1NPC1 | |
| SCHEMBL4106292 | 0.71 | ALDH1A1 (0.71) | LMNAKMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL25986986 | 0.71 | SMN1; SMN2 (0.65) | KMT2AALDH1A1NPC1SMN1; SMN2MEN1 | |
| SCHEMBL25208513 | 0.70 | CES2 (0.53) | KMT2AALDH1A1MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |