Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943923 | 0.78 | PDK1 (0.56) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL2645378 | 0.78 | PDK1 (0.56) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL483352 | 0.75 | PI4KA (0.46) | MEN1KMT2AKDM4EALDH1A1CASP1 | |
| SCHEMBL16264544 | 0.71 | KDM4E (0.46) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL3892806 | 0.70 | KDM4E (0.53) | MEN1KMT2AKDM4ELMNAMCL1 | |
| SCHEMBL352470 | 0.70 | KDM4E (0.53) | MEN1KMT2AKDM4ELMNAMCL1 | |
| SCHEMBL8681504 | 0.69 | ALDH1A1 (0.53) | MEN1KMT2AKDM4ELMNAMCL1 | |
| SCHEMBL483604 | 0.68 | RIPK1 (0.38) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL22777775 | 0.68 | MAP4K4 (0.43) | KDM4ELMNA | |
| SCHEMBL31229583 | 0.67 | MAPT (0.35) | MEN1KMT2AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312794-B1 | THIAZETIDINE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0312794-A1 | Thiazetidine derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-04-26 | — | — | EP | disclosed |