Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943923 | 1.00 | PDK1 (0.56) | PDK1CYP2C9POLBNPC1ALDH1A1 | |
| SCHEMBL5797987 | 0.84 | PDK1 (0.54) | PDK1CYP2C9POLBNPC1ALDH1A1 | |
| SCHEMBL24960020 | 0.80 | ALDH1A1 (0.60) | PDK1CYP2C9POLBNPC1ALDH1A1 | |
| SCHEMBL9537013 | 0.78 | MEN1 (0.46) | PDK1POLBNPC1ALDH1A1KDM4E | |
| SCHEMBL5138748 | 0.77 | PDK1 (0.58) | PDK1POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL16264455 | 0.77 | CYP2C9 (0.58) | PDK1CYP2C9POLBNPC1ALDH1A1 | |
| SCHEMBL9211341 | 0.74 | PDK1 (0.59) | PDK1POLBALDH1A1KDM4EMAPT | |
| SCHEMBL31229583 | 0.74 | MAPT (0.35) | NPC1ALDH1A1RAB9AKDM4EMAPT | |
| SCHEMBL2176039 | 0.73 | PDK1 (0.58) | PDK1POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL29390917 | 0.73 | PDK1 (0.58) | PDK1POLBNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111388443-B | Cellulose empty capsule and capsule thereof | 上海祺宇生物科技有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-111388443-A | Cellulose empty capsule and capsule thereof | 上海祺宇生物科技有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-115885033-A | Bacterial strain belonging to the genus bacillus and microbial control agent using the same | 国立大学法人东海国立大学机构 | 2023-03-31 | — | — | CN | disclosed |
| CN-115044025-A | Polyester type high polymer material and preparation method and application thereof | 中兴通讯股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-110158199-B | Preparation method of biomass fiber capable of shielding ultraviolet rays | 闽江学院 | 2022-05-13 | — | — | CN | disclosed |
| CN-110158199-B | Preparation method of biomass fiber capable of shielding ultraviolet rays | 闽江学院 | 2022-05-13 | — | — | CN | disclosed |
| CN-111388443-B | Cellulose empty capsule and capsule thereof | 上海祺宇生物科技有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-107987248-B | Polyurethane capable of inducing luminescence and preparation method thereof | 中国科学院深圳先进技术研究院 | 2020-11-03 | — | — | CN | disclosed |
| CN-111388443-A | Cellulose empty capsule and capsule thereof | 上海祺宇生物科技有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-110158199-A | Preparation method of biomass fiber capable of shielding ultraviolet rays | 闽江学院 | 2019-08-23 | — | — | CN | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-20160194299-A1 | COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2016-07-07 | — | — | US | disclosed |
| US-20160194299-A1 | COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2016-07-07 | — | — | US | disclosed |
| WO-2014190199-A1 | COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-11-27 | — | — | WO | disclosed |
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194299-A1 | COMPOUNDS FOR TREATMENT OF DRUG RESISTANT AND PERSISTENT TUBERCULOSIS | FNTB, PGLS, EP300 | PDK1 3308/4885CYP2C9 1792/4885POLB 863/4885 |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | GCK, GCKR, HK1 | PDK1 137/4885CYP2C9 3244/4885POLB 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.