Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167993 | 0.91 | HTR7 (0.54) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL10648046 | 0.84 | KCNH2 (0.53) | DRD2HTR7KCNH2SLC6A2SLC6A3 | |
| SCHEMBL2094771 | 0.84 | KCNH2 (0.50) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL28481556 | 0.84 | DRD2 (0.68) | DRD2DRD3HTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL10574028 | 0.83 | KCNH2 (0.51) | DRD2HTR7KCNH2SLC6A2SLC6A3 | |
| SCHEMBL20699709 | 0.82 | BPTF (0.54) | HTR1AHTR7 | |
| SCHEMBL10373948 | 0.82 | BPTF (0.54) | HTR1AHTR7 | |
| SCHEMBL1598706 | 0.82 | DRD2 (0.74) | DRD2DRD3HTR7KCNH2OPRM1 | |
| SCHEMBL520966 | 0.82 | ADRA2C (0.62) | DRD2DRD3HTR1AHTR7KCNH2 | |
| SCHEMBL5178875 | 0.81 | KCNH2 (0.57) | DRD2DRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254623-B1 | AMINOALKYLTHIO TRIAZOLOPYRIDINE OR TRIAZOLOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY USEFUL AS ANTALGICS | LABORATOIRES UPSA (FR) | 1993-06-09 | — | — | EP | disclosed |
| US-4886805-A | Novel aminoalkylthio derivatives of triazolopyridine or triazoloquinoline, the processes for their preparation, and drugs, useful especially as analgesics, in which they are present | Centre D'Activite Et De Recherches Pharmaceutique Industrielle Biologique Medicale (FR) | 1989-12-12 | — | — | US | disclosed |
| EP-0254623-A1 | Aminoalkylthio triazolopyridine or triazoloquinoline derivatives, process for their preparation, medicaments containing them, particularly useful as antalgics | LABORATOIRES UPSA (FR) | 1988-01-27 | — | — | EP | disclosed |