Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 8/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535373 | 0.90 | KMT2A (0.49) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9539535 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9241429 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1POLBLMNAMEN1 | |
| SCHEMBL9537199 | 0.83 | LMNA (0.61) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9536182 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1POLBPIM1LMNA | |
| SCHEMBL9534341 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1POLBLMNAMEN1 | |
| SCHEMBL9693352 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9757311 | 0.82 | LMNA (0.53) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9869412 | 0.81 | TOP2A (0.61) | ALDH1A1POLBKMT2ATOP1TOP2A | |
| SCHEMBL9757188 | 0.81 | HPGD (0.55) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |