Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637205 | 0.79 | DDB1 (0.55) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL318066 | 0.78 | MAPK1 (0.56) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL15874734 | 0.78 | MAPK1 (0.56) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL11818914 | 0.77 | GAA (0.41) | DDB1CRBNALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1750687 | 0.77 | LMNA (0.38) | DDB1CRBNCYP3A4ALDH1A1CYP19A1 | |
| SCHEMBL1751794 | 0.77 | DDB1 (0.50) | DDB1CRBNCYP19A1KMT2ATP53 | |
| SCHEMBL11873333 | 0.77 | MAPK1 (0.55) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL1506570 | 0.75 | ESR2 (0.58) | DDB1CRBNALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10451354 | 0.73 | DDB1 (0.49) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL11821931 | 0.73 | HTR2C (0.41) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123127-A1 | REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES | EVERON BIOSCIENCES, INC. | 2020-04-23 | — | — | US | disclosed |
| WO-2017189553-A1 | REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES | EVERON BIOSCIENCES, INC. (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-0291114-B1 | OXIMINO ETHER COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-25 | — | — | EP | disclosed |
| US-4921524-A | HERBICIDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1990-05-01 | — | — | US | disclosed |
| EP-0291114-A2 | Oximino ether compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123127-A1 | REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES | CD68, CD47, ARG1 | DDB1 1200/4885CRBN 1539/4885CYP3A4 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.