Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.33 |
| ▸ | MC5R | P33032 | 2/20 | 0.33 |
| ▸ | MC3R | P41968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537377 | 1.00 | CCKBR (0.35) | CCKBRMC4RMC5RMC3R | |
| SCHEMBL14244789 | 0.88 | CNR1 (0.36) | — | |
| SCHEMBL9903272 | 0.83 | APOBEC3A (0.31) | — | |
| Hydrochloric Acid SCHEMBL721032 | 0.81 | DNM1 (0.40) | — | |
| SCHEMBL18408792 | 0.79 | LTA4H (0.36) | — | |
| SCHEMBL15228058 | 0.78 | XDH (0.39) | — | |
| SCHEMBL15668776 | 0.78 | — | — | |
| SCHEMBL3632927 | 0.77 | — | — | |
| SCHEMBL19891851 | 0.77 | CA1 (0.36) | — | |
| SCHEMBL15348708 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480969-A4 | AMINO ACID ANALOG CCK ANTAGONISTS | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0480969-A1 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | disclosed |