Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CCR9 | P51686 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624571 | 0.83 | SMN1; SMN2 (0.53) | AKR1C3AKR1C2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3249787 | 0.80 | ALDH1A1 (0.53) | FLT1FLT4KDRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9536549 | 0.80 | PRKCI (0.49) | FLT1FLT4KDRAKR1C3AKR1C2 | |
| SCHEMBL9657574 | 0.79 | PTGS1 (0.60) | FLT1FLT4KDRAKR1C3AKR1C2 | |
| SCHEMBL9538398 | 0.79 | PTGS1 (0.55) | FLT1FLT4KDRAKR1C3AKR1C2 | |
| SCHEMBL14906059 | 0.78 | MCL1 (0.61) | SMN1; SMN2HPGDPTGS1PTGS2TSHR | |
| SCHEMBL8098757 | 0.77 | CA2 (0.50) | HPGDPTGS1PTGS2TSHRMCL1 | |
| SCHEMBL11560825 | 0.76 | MCL1 (0.59) | SMN1; SMN2HPGDPTGS1PTGS2TSHR | |
| SCHEMBL9535652 | 0.76 | PTGS2 (0.54) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9658156 | 0.76 | PTGS1 (0.48) | FLT1FLT4KDRAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |