Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.40 |
| ▸ | ITGAL | P20701 | 7/20 | 0.40 |
| ▸ | USP7 | Q93009 | 3/20 | 0.40 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539520 | 0.86 | ALDH1A1 (0.45) | PTGS1PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9538401 | 0.85 | ALDH1A1 (0.44) | PTGS1PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6598563 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2ALDH1A1MEN1MAPT | |
| SCHEMBL9539406 | 0.80 | PTGS1 (0.54) | PTGS1PTGS2ALDH1A1MEN1MAPT | |
| SCHEMBL4575696 | 0.79 | PTGS1 (0.56) | PTGS1PTGS2ITGB2ICAM1ITGAL | |
| SCHEMBL9537401 | 0.79 | FLT1 (0.44) | PTGS1PTGS2FLT1FLT4KDR | |
| SCHEMBL9536230 | 0.78 | PTGS2 (0.55) | PTGS1PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9535010 | 0.77 | PTGS2 (0.54) | PTGS1PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9624571 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AAKR1C3 | |
| SCHEMBL9535361 | 0.77 | ITGB2 (0.50) | ALDH1A1MEN1MAPTKMT2AITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |