Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540615 | 0.87 | SIGMAR1 (0.48) | SIGMAR1BCHEOPRM1TMEM97OPRD1 | |
| SCHEMBL9537715 | 0.87 | ACHE (0.52) | SIGMAR1BCHEACHEEBP | |
| SCHEMBL9541201 | 0.84 | ACHE (0.38) | BCHEACHE | |
| Bromide SCHEMBL9538514 | 0.83 | ACHE (0.37) | BCHEACHE | |
| SCHEMBL9538614 | 0.83 | ACHE (0.37) | SIGMAR1BCHEACHEOPRM1OPRD1 | |
| Bromide SCHEMBL9539133 | 0.82 | ACHE (0.37) | SIGMAR1BCHEACHEOPRM1OPRD1 | |
| SCHEMBL9538866 | 0.82 | BCHE (0.41) | SIGMAR1BCHEACHEOPRM1TMEM97 | |
| SCHEMBL9540887 | 0.82 | ACHE (0.58) | BCHEACHEOPRM1OPRK1 | |
| SCHEMBL9538266 | 0.81 | OPRD1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL2457355 | 0.81 | OPRD1 (0.42) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |