Glucuronate

Glucuronate

SCHEMBL9537745

CCCCCCCCCCCCc1cc2nc3ccccc3oc-2cc1=O.O=C(O)[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPSE Q9Y251 8/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 4/20 0.41
KMT2A Q03164 4/20 0.41
POLB P06746 3/20 0.41
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
FAAH O00519 3/20 0.38
HSD17B10 Q99714 2/20 0.38
CES1 P23141 2/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862517 0.84 MAPT (0.55) ALDH1A1MAPTKMT2APOLBMEN1
Glucuronate SCHEMBL9538374 0.78 APP (0.43) HPSECYP1A2
Glucuronate SCHEMBL2310793 0.77 APP (0.47) ALDH1A1MAPTKMT2APOLBMEN1
Glucuronate SCHEMBL2308415 0.77 APP (0.47) ALDH1A1MAPTKMT2APOLBMEN1
SCHEMBL3862519 0.73 APP (0.52) ALDH1A1MAPTKMT2APOLBMEN1
SCHEMBL9540346 0.73 APP (0.52) ALDH1A1MAPTKMT2APOLBMEN1
SCHEMBL9538491 0.72 PTPN1 (0.50) HPSEALDH1A1MAPTKMT2AMEN1
SCHEMBL9539379 0.72 PTPN1 (0.50) HPSEALDH1A1MAPTKMT2AMEN1
SCHEMBL14141884 0.69 APP (0.47) ALDH1A1MAPTKMT2APOLBMEN1
Flavone SCHEMBL6561748 0.67 TNKS (0.62) ALDH1A1MAPTKMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242805-A Useful in directingcells producing enzymes that hydrolyze the glycoside MOLECULAR PROBES, INC. (US) 1993-09-07 US disclosed