Sugi Predict

Sugi Predict / Compounds / Glucuronate

Glucuronate

Glucuronate

SCHEMBL9538374

CCCCCCCCCCCCc1ccc2nc3ccc(=O)cc-3oc2c1.O=C(O)[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 12/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ HPSE Q9Y251 4/20 0.38
▸ EIF4A1 P60842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601681 0.84 APP (0.58) APPCYP1A2EIF4A1
SCHEMBL738742 0.83 APP (0.59) APPCYP1A2EIF4A1
Glucuronate SCHEMBL2310793 0.79 APP (0.47) APPCYP1A2
Glucuronate SCHEMBL2308415 0.79 APP (0.47) APPCYP1A2
Glucuronate SCHEMBL9537745 0.78 HPSE (0.41) CYP1A2HPSE
SCHEMBL5710520 0.77 APP (0.55) APPCYP1A2
SCHEMBL5681747 0.77 APP (0.55) APPCYP1A2
SCHEMBL4922053 0.75 APP (0.57) APPCYP1A2
SCHEMBL5710642 0.74 APP (0.54) APPCYP1A2
SCHEMBL3104713 0.74 APP (0.55) APPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242805-A Useful in directingcells producing enzymes that hydrolyze the glycoside MOLECULAR PROBES, INC. (US) 1993-09-07 — — US disclosed
WO-1993004074-A1 LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES MOLECULAR PROBES, INC. (US) 1993-03-04 — — WO disclosed