Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL18894321 | 0.99 | APP (0.58) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL563769 | 0.82 | APP (0.66) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL10167845 | 0.82 | APP (0.68) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL10208641 | 0.80 | APP (0.64) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL18641343 | 0.80 | APP (0.63) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL6998321 | 0.79 | APP (0.67) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL1094100 | 0.79 | APP (0.59) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL24179877 | 0.79 | APP (0.72) | APPCYP1A2ALDH1A1GAAHPGD | |
| SCHEMBL7002876 | 0.77 | APP (0.66) | APPCYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL738742 | 0.77 | APP (0.59) | APPCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242805-A | Useful in directingcells producing enzymes that hydrolyze the glycoside | MOLECULAR PROBES, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993004074-A1 | LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |