Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535652 | 0.86 | PTGS2 (0.54) | MAPTPTGS2SMN1; SMN2GAAMEN1 | |
| SCHEMBL9534367 | 0.80 | PTGS2 (0.55) | CA1CA2MAPTPTGS2SMN1; SMN2 | |
| SCHEMBL10625554 | 0.78 | CA2 (0.66) | CA1CA2PTGS2PTGS1KMT2A | |
| SCHEMBL9538256 | 0.77 | HDAC1 (0.49) | MAPTSMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL9539469 | 0.75 | PTGS2 (0.53) | PTGS2SMN1; SMN2GAAACLYNPC1 | |
| SCHEMBL9534404 | 0.74 | PTGS2 (0.55) | PTGS2SMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL16535694 | 0.73 | PTGS1 (0.44) | PTGS2SMN1; SMN2PTGS1MEN1ALDH1A1 | |
| SCHEMBL9539498 | 0.72 | AKR1C3 (0.53) | MAPTSMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL3524776 | 0.72 | CA2 (0.57) | CA1CA2SMN1; SMN2GAAMEN1 | |
| SCHEMBL13719926 | 0.71 | CA2 (0.57) | CA1CA2SMN1; SMN2GAAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |