Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535897 | 0.87 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL9535652 | 0.80 | PTGS2 (0.54) | SMN1; SMN2MAPTMEN1ALDH1A1POLB | |
| SCHEMBL9539498 | 0.79 | AKR1C3 (0.53) | SMN1; SMN2MAPTMEN1ALDH1A1POLB | |
| SCHEMBL9538281 | 0.77 | CA1 (0.44) | SMN1; SMN2MAPTMEN1ALDH1A1POLB | |
| SCHEMBL9536549 | 0.74 | PRKCI (0.49) | HDAC1PRKCIHDAC2SMN1; SMN2MAPT | |
| SCHEMBL15638643 | 0.74 | ALDH1A1 (0.47) | HDAC1SMN1; SMN2MAPTALDH1A1ALOX12 | |
| SCHEMBL121984 | 0.74 | PRKCI (0.59) | HDAC1PRKCIHDAC3HDAC2NCOR2 | |
| SCHEMBL27111060 | 0.73 | PRKCI (0.73) | HDAC1PRKCIHDAC3HDAC2MAPT | |
| SCHEMBL17676671 | 0.73 | PRKCI (0.58) | HDAC1PRKCIHDAC3HDAC2MAPT | |
| SCHEMBL11542046 | 0.73 | MAOB (0.48) | HDAC1PRKCIHDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |