Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GNG2 | P59768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708020 | 0.83 | FTO (0.66) | FTOMEN1MAPTKMT2AHTT | |
| SCHEMBL9538912 | 0.81 | FTO (0.69) | FTOMEN1MAPTKMT2AHTT | |
| Dichlorofluorescein SCHEMBL30606648 | 0.80 | MAPT (0.64) | FTOMEN1MAPTKMT2AHTT | |
| Dichlorofluorescein SCHEMBL29364373 | 0.80 | MAPT (0.64) | FTOMEN1MAPTKMT2AHTT | |
| Dichlorofluorescein SCHEMBL157703 | 0.80 | MAPT (0.64) | FTOMEN1MAPTKMT2AHTT | |
| SCHEMBL938920 | 0.80 | DHFR (0.39) | FTOMEN1MAPTKMT2AHTT | |
| Dichlorofluorescein SCHEMBL25207800 | 0.79 | MAPT (0.63) | FTOMEN1MAPTKMT2AHTT | |
| SCHEMBL1470877 | 0.79 | GSTP1 (0.60) | FTOMEN1MAPTKMT2AHTT | |
| SCHEMBL29371871 | 0.79 | FTO (0.47) | FTOMEN1MAPTKMT2AHTT | |
| SCHEMBL1299465 | 0.79 | FTO (0.47) | FTOMEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208148-A | Leuco xanthene dyes | MOLECULAR PROBES, INC. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0185547-B1 | POLYNUCLEOTIDE HYBRIDIZATION ASSAYS EMPLOYING CATALYZED LUMINESCENCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |