SCHEMBL9727271

SCHEMBL9727271

COC(=O)C1CCCN1C(=O)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
P2RX7 Q99572 9/20 0.47
KMT2A Q03164 2/20 0.47
SIGMAR1 Q99720 1/20 0.45
ENPP2 Q13822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30546762 0.89 P2RX7 (0.61) ALDH1A1P2RX7
SCHEMBL30546740 0.89 P2RX7 (0.61) ALDH1A1P2RX7
SCHEMBL9538607 0.85 ALDH1A1 (0.52) ALDH1A1P2RX7KMT2ASIGMAR1
SCHEMBL9727236 0.85 TSHR (0.57) ALDH1A1P2RX7KMT2ASIGMAR1
SCHEMBL9727467 0.84 ALDH1A1 (0.55) ALDH1A1
SCHEMBL9537062 0.83 ALDH1A1 (0.50) ALDH1A1P2RX7KMT2ASIGMAR1
SCHEMBL9727517 0.80 ALDH1A1 (0.55) ALDH1A1KMT2A
SCHEMBL9727327 0.79 ALDH1A1 (0.54) ALDH1A1
SCHEMBL9727437 0.78 ALDH1A1 (0.48) ALDH1A1
SCHEMBL8877185 0.77 ALDH1A1 (0.47) ALDH1A1KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142065-A Intermediates for herbicides, fungicides, miticides and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091537-A Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4985063-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed