Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386571 | 0.82 | MEN1 (0.53) | TDP1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL2461665 | 0.81 | GPR35 (0.64) | GPR35ERN1TDP1MAPTCRHBP | |
| SCHEMBL201556 | 0.78 | GABRA1 (0.48) | LMNAL3MBTL1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9538353 | 0.78 | ALDH1A1 (0.45) | GPR35TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL15452483 | 0.77 | TDP1 (0.52) | GPR35TDP1MAPTL3MBTL1RECQL | |
| SCHEMBL10782520 | 0.77 | GPR35 (0.51) | GPR35TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL9539174 | 0.77 | ALDH1A1 (0.49) | TDP1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL1398094 | 0.76 | ALDH1A1 (0.43) | GPR35TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL1077970 | 0.75 | GPR35 (1.00) | GPR35ERN1TDP1MAPTCRHBP | |
| SCHEMBL4854222 | 0.75 | GPR35 (0.67) | GPR35ERN1TDP1MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005012-A1 | NEW COMPOUNDS | AB ASTRA (SE) | 1993-03-18 | — | — | WO | disclosed |
| EP-0530166-A2 | 3-Hydroxy anthranilic acid derivatives for inhibiting 3-hydroxy anthranilate oxygenase | Astra Aktiebolag (SE) | 1993-03-03 | — | — | EP | disclosed |