Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537176 | 0.87 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL9534367 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1CA2CA1LMNA | |
| SCHEMBL9536821 | 0.76 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL9536981 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL9537156 | 0.72 | ADRB3 (0.52) | PTGS2PTGS1 | |
| SCHEMBL10625554 | 0.72 | CA2 (0.66) | PTGS2PTGS1CA2CA1LMNA | |
| SCHEMBL19333346 | 0.69 | CA2 (0.47) | PTGS2PTGS1CA2CA1POLB | |
| SCHEMBL9539328 | 0.68 | PTGS2 (0.50) | PTGS2PTGS1LMNAPOLBMAPK14 | |
| SCHEMBL9537442 | 0.68 | PTGS2 (0.58) | PTGS2PTGS1LMNA | |
| SCHEMBL9537417 | 0.68 | PTGS2 (0.55) | PTGS2PTGS1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |