Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700903 | 0.84 | ALDH1A1 (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9540664 | 0.82 | TACR1 (0.55) | TACR1TACR3 | |
| SCHEMBL9540669 | 0.82 | TACR1 (0.55) | TACR1TACR3 | |
| SCHEMBL9538871 | 0.82 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9540182 | 0.80 | KDM4E (0.41) | KMT2AKDM4EL3MBTL1TACR1TACR3 | |
| SCHEMBL9538885 | 0.80 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9538450 | 0.80 | KDM4E (0.42) | KMT2AKDM4EL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL9538034 | 0.73 | TACR3 (0.54) | TACR1TACR3 | |
| SCHEMBL9338635 | 0.72 | TACR1 (0.55) | TACR1TACR3 | |
| SCHEMBL9539374 | 0.66 | TACR3 (0.45) | KMT2AKDM4EL3MBTL1TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |