Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539141 | 0.88 | ITGB3 (0.46) | TACR3ENPP2NPY5RITGB3ITGA2B | |
| SCHEMBL7670973 | 0.83 | NPY5R (0.46) | TACR3NPY5RITGB3ITGA2BKDM4E | |
| SCHEMBL9539370 | 0.82 | ENPP2 (0.43) | ENPP2NPY5RCTRCRENMMP2 | |
| SCHEMBL9539144 | 0.79 | ENPP2 (0.45) | ENPP2NPY5RRENLPAR1LPAR3 | |
| SCHEMBL9699592 | 0.75 | TACR3 (0.40) | TACR3NPY5RITGB3ITGA2BTACR1 | |
| SCHEMBL9698397 | 0.74 | ITGB3 (0.39) | TACR3NPY5RITGB3ITGA2BTACR1 | |
| SCHEMBL7670805 | 0.73 | TACR1 (0.44) | TACR3NPY5RKDM4EKMT2ATACR1 | |
| SCHEMBL7665676 | 0.72 | TACR3 (0.43) | TACR3NPY5RTACR1 | |
| SCHEMBL9338635 | 0.70 | TACR1 (0.55) | TACR3TACR1 | |
| SCHEMBL9540182 | 0.69 | KDM4E (0.41) | TACR3KDM4EKMT2AL3MBTL1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |