Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.31 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.31 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526599 | 0.75 | KCNA4 (0.38) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL9537044 | 0.70 | MEN1 (0.35) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL16429623 | 0.70 | MEN1 (0.35) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL7313249 | 0.66 | FBP1 (0.36) | MEN1CYP2C19KMT2A | |
| SCHEMBL3992251 | 0.64 | KDM1A (0.36) | — | |
| SCHEMBL29033525 | 0.63 | KDM1A (0.34) | — | |
| SCHEMBL1153469 | 0.62 | KDM1A (0.44) | — | |
| SCHEMBL28001232 | 0.62 | KMT2A (0.38) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL10674140 | 0.62 | KDM1A (0.38) | — | |
| SCHEMBL734440 | 0.62 | KDM1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |