Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526599 | 0.78 | KCNA4 (0.38) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL16429623 | 0.73 | MEN1 (0.35) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL4811637 | 0.73 | — | — | |
| SCHEMBL9539166 | 0.70 | MEN1 (0.35) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL6903379 | 0.70 | MEN1 (0.36) | MEN1CYP2C19KMT2AKCNA4KCNA1 | |
| SCHEMBL505429 | 0.69 | EDNRA (0.32) | CYP2C19POLBL3MBTL1 | |
| SCHEMBL7313249 | 0.69 | FBP1 (0.36) | MEN1CYP2C19KMT2AFBP1ALDH1A1 | |
| SCHEMBL11799775 | 0.69 | — | — | |
| SCHEMBL5170532 | 0.68 | POLB (0.35) | MEN1KMT2APOLBUSP2 | |
| SCHEMBL6708456 | 0.68 | ALDH1A1 (0.33) | MEN1CYP2C19KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |