Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949480 | 0.82 | CTSA (0.30) | CTSA | |
| SCHEMBL949999 | 0.80 | APP (0.36) | APPEPHX1CTSA | |
| SCHEMBL953932 | 0.71 | CAPN1 (0.34) | — | |
| SCHEMBL17335564 | 0.70 | PARP1 (0.34) | CTSA | |
| SCHEMBL949482 | 0.69 | MPO (0.36) | — | |
| SCHEMBL953933 | 0.68 | CYP3A4 (0.40) | — | |
| SCHEMBL17335530 | 0.67 | APP (0.36) | APP | |
| SCHEMBL7383797 | 0.66 | SLC9A1 (0.31) | SLC9A1 | |
| SCHEMBL17335566 | 0.65 | PARP1 (0.37) | CTSA | |
| SCHEMBL12479410 | 0.65 | CASP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |