Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953932 | 0.92 | CAPN1 (0.34) | MPOSLC6A4CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL956333 | 0.81 | PLA2G10 (0.37) | MPOFAAH | |
| SCHEMBL954663 | 0.77 | MPO (0.40) | MPOSLC6A4 | |
| SCHEMBL950000 | 0.73 | FFAR1 (0.39) | — | |
| SCHEMBL953930 | 0.69 | APP (0.35) | — | |
| SCHEMBL949484 | 0.68 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL949480 | 0.68 | CTSA (0.30) | — | |
| SCHEMBL10678782 | 0.67 | TBXAS1 (0.33) | MPO | |
| SCHEMBL19438593 | 0.66 | CAPN1 (0.46) | MPOSLC6A4 | |
| SCHEMBL953933 | 0.66 | CYP3A4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |