Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401012 | 0.86 | KMT2A (0.35) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL10400910 | 0.85 | PDE4B (0.37) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL9536988 | 0.85 | SMN1; SMN2 (0.37) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL10400747 | 0.84 | KMT2A (0.33) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL10401051 | 0.82 | PDE4B (0.35) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL9536239 | 0.82 | SMN1; SMN2 (0.35) | KMT2APDE4BPDE4DACHEBCHE | |
| SCHEMBL10401013 | 0.80 | PDE4B (0.35) | PDE4BPDE4DHTTATM | |
| SCHEMBL9538050 | 0.76 | ACHE (0.40) | PDE4BACHEBCHETDP1HTT | |
| SCHEMBL10400124 | 0.74 | LMNA (0.34) | KMT2AHTTATMLMNAMEN1 | |
| SCHEMBL10400122 | 0.74 | TAS1R3 (0.34) | KMT2AHTTATMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |