Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005448 | 0.90 | TYR (0.46) | ADRB2TYRLMNAHTTTRPA1 | |
| SCHEMBL1006118 | 0.87 | CHRNA7 (0.52) | CHRNA7LMNAACHEALOX5 | |
| SCHEMBL3474726 | 0.85 | ESR1 (0.62) | ESR1PDCD1ESR2CD274TYR | |
| SCHEMBL1006001 | 0.85 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL1005314 | 0.85 | IDO1 (0.42) | HTTACHE | |
| SCHEMBL14737295 | 0.85 | IDO1 (0.42) | HTTACHE | |
| SCHEMBL3745333 | 0.85 | ADRB2 (0.56) | ADRB2LMNA | |
| SCHEMBL3754314 | 0.85 | ADRB2 (0.56) | ADRB2LMNA | |
| SCHEMBL6556654 | 0.85 | ACACB (0.37) | ESR1PDCD1ESR2CD274 | |
| SCHEMBL1003900 | 0.85 | ADRB2 (0.56) | ADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307332-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | UNIV CASE WESTERN RESERVE (US) | 2024-09-19 | — | — | US | claimed |
| US-11833124-B2 | Compositions and methods for modulating HEXIM1 expression | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-12-05 | — | — | US | claimed |
| US-20210212969-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | CLEVELAND STATE UNIVERSITY | 2021-07-15 | — | — | US | claimed |
| US-20160346236-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXM1 EXPRESSION | CLEVELAND STATE UNIVERSITY | 2016-12-01 | — | — | US | claimed |
| WO-2015116968-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-08-06 | — | — | WO | claimed |
| US-20240307332-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | UNIV CASE WESTERN RESERVE (US) | 2024-09-19 | — | — | US | disclosed |
| US-11833124-B2 | Compositions and methods for modulating HEXIM1 expression | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-20210212969-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | CLEVELAND STATE UNIVERSITY | 2021-07-15 | — | — | US | disclosed |
| US-10959966-B2 | Compositions and methods for modulating HEXM1 expression | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20160346236-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXM1 EXPRESSION | CLEVELAND STATE UNIVERSITY | 2016-12-01 | — | — | US | disclosed |
| WO-2015195684-A2 | SMALL MOLECULE ANTI-SCARRING AGENTS | UNIVERSITY OF ROCHESTER (US) | 2015-12-23 | — | — | WO | disclosed |
| WO-2015116968-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-08-06 | — | — | WO | disclosed |
| WO-1993002041-A1 | ESTER-CONTAINING QUATERNARY AMMONIUM SALTS | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| US-RE32618-E | ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| US-4308199-A | ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10959966-B2 | Compositions and methods for modulating HEXM1 expression | HEXB, HEXA, MYADM | ESR1 4250/4885PDCD1 3085/4885ESR2 3587/4885 |
| US-20210212969-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | HK1, HKDC1, HEXB | ESR1 4723/4885PDCD1 3102/4885ESR2 3997/4885 |
| US-11833124-B2 | Compositions and methods for modulating HEXIM1 expression | HK1, HKDC1, HEXB | ESR1 4723/4885PDCD1 3102/4885ESR2 3997/4885 |
| US-20160346236-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXM1 EXPRESSION | HEXB, HEXA, MYADM | ESR1 4250/4885PDCD1 3085/4885ESR2 3587/4885 |
| US-20240307332-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | HK1, HKDC1, HEXB | ESR1 4723/4885PDCD1 3102/4885ESR2 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.