Sugi Predict

Sugi Predict / Compounds / SCHEMBL1005448

SCHEMBL1005448

SCHEMBL1005448

[CH2]C(C)c1ccc(C(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 2/20 0.46
▸ HTT P42858 2/20 0.42
▸ IDO1 P14902 2/20 0.41
▸ MGLL Q99685 1/20 0.39
▸ NISCH Q9Y2I1 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CYP2C9 P11712 3/20 0.38
▸ HIF1A Q16665 2/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ PYCR1 P32322 1/20 0.38
▸ TRPA1 O75762 1/20 0.37
▸ PTGS1 P23219 1/20 0.37
▸ CACNA1C Q13936 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ ADRB2 P07550 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9539624 0.90 ESR1 (0.38) TYRHTTLMNATRPA1PTGS1
SCHEMBL104124 0.83 TYR (0.58) TYRHTTIDO1MGLLLMNA
SCHEMBL3754314 0.82 ADRB2 (0.56) IDO1LMNAHIF1AMAPK1HPGD
SCHEMBL1003900 0.82 ADRB2 (0.56) IDO1LMNAHIF1AMAPK1HPGD
SCHEMBL3745333 0.82 ADRB2 (0.56) IDO1LMNAHIF1AMAPK1HPGD
SCHEMBL25304239 0.80 ADRB2 (0.54) IDO1LMNAHIF1AMAPK1HPGD
SCHEMBL28912214 0.79 TYR (0.55) TYRHTTIDO1MGLLNISCH
Ammonia Solution, Strong SCHEMBL7550588 0.79 TYR (0.55) TYRHTTIDO1MGLLLMNA
Water SCHEMBL29278796 0.79 TYR (0.55) TYRHTTIDO1MGLLLMNA
Water SCHEMBL11726962 0.79 TYR (0.55) TYRHTTIDO1MGLLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140275463-A1 ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME CHISSO PETROCHEMICAL CORPORATION (JP) 2014-09-18 — — US disclosed
EP-1548020-B1 SILICON COMPOUND JNC CORP (JP) 2014-07-23 — — EP disclosed
US-8367792-B2 Polysiloxane compound and method of producing the same JNC CORPORATION (JP) 2013-02-05 — — US disclosed
US-20120208973-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME OOTAKE NOBUMASA (JP) 2012-08-16 — — US disclosed
EP-1550664-B1 SILICON COMPOUND JNC CORP (JP) 2012-06-27 — — EP disclosed
US-8173758-B2 Polysiloxane compound and method of producing the same JNC CORPORATION (JP) 2012-05-08 — — US disclosed
US-20110178313-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME OOTAKE NOBUMASA 2011-07-21 — — US disclosed
US-7964692-B2 Polymer obtained by addition-polymerization initiated by a silicon compound JNC CORPORATION (JP) 2011-06-21 — — US disclosed
US-7939617-B2 Silsesquioxane derivative; electronic material, optical material, optoelectronic material, paint, and primer. CHISSO CORPORATION (JP) 2011-05-10 — — US disclosed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 — — US disclosed
EP-1548020-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-06-29 — — EP disclosed
US-20050033077-A1 Production process for silicon compound and the same JNC CORPORATION (JP) 2005-02-10 — — US disclosed
US-20040249103-A1 Silsesquioxane derivatives and process for production thereof JNC CORPORATION (JP) 2004-12-09 — — US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 — — US disclosed
EP-1428795-A1 SILSESQUIOXANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF CHISSO CORPORATION (JP) 2004-06-16 — — EP disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 — — US disclosed
US-20040030084-A1 Production process for silsesquioxane derivative and silsesquioxane derivative JNC CORPORATION (JP) 2004-02-12 — — US disclosed
CN-1374973-A Catalyst system and process for olefin polymerization BASSER TECHNOLOGY N V (NL) 2002-10-16 — — CN disclosed
EP-0104146-B1 COLOUR-PHOTOGRAPHIC RECORDING MATERIAL CIBA-GEIGY AG (CH) 1986-07-30 — — EP disclosed
US-4465757-A PYRIDINE STABILIZERS CIBA-GEIGY A.G. (CH) 1984-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178313-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME RPS4X, POLR2A, MSL1 TYR 4823/4885HTT 2439/4885IDO1 4256/4885
US-20140275463-A1 ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME PIEZO1, PFAS, MCM6 TYR 3813/4885HTT 4056/4885IDO1 4399/4885
US-20120208973-A1 POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME RPS4X, POLR2A, MSL1 TYR 4823/4885HTT 2439/4885IDO1 4256/4885
US-20050033077-A1 Production process for silicon compound and the same STS, SMS, SFXN1 TYR 1902/4885HTT 2666/4885IDO1 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.