Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539562 | 0.90 | DUT (0.40) | DUTMTNR1AMTNR1B | |
| SCHEMBL9538765 | 0.88 | DUT (0.39) | DUTMTNR1AHRH3LOXL2MTNR1B | |
| SCHEMBL9093167 | 0.82 | DUT (0.34) | DUTMTNR1AMTNR1B | |
| SCHEMBL14745993 | 0.77 | IDO1 (0.39) | DUTMTNR1AHRH3LOXL2MTNR1B | |
| SCHEMBL25429760 | 0.76 | DUT (0.40) | DUTHRH3 | |
| SCHEMBL31609648 | 0.76 | DUT (0.40) | DUTHRH3 | |
| SCHEMBL75303 | 0.74 | LOXL2 (0.45) | MTNR1AHRH3LOXL2MTNR1B | |
| SCHEMBL1770246 | 0.72 | NR3C1 (0.41) | DUT | |
| SCHEMBL6595669 | 0.71 | CYP19A1 (0.41) | — | |
| SCHEMBL30019343 | 0.68 | NR3C1 (0.42) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005058-A1 | O-HETEROARYL, O-ALKYLHETEROARYL, O-ALKENYLHETEROARYL AND O-ALKYNYLHETEROARYLMACROLIDES | MERCK & CO., INC. (US) | 1993-03-18 | — | — | WO | disclosed |