Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538825 | 0.86 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9542445 | 0.85 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9584565 | 0.85 | NPC1 (0.41) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9585400 | 0.79 | ALDH1A1 (0.39) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9538817 | 0.79 | LMNA (0.48) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL9541331 | 0.79 | TRPM8 (0.40) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9539802 | 0.79 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1POLBTSHR | |
| SCHEMBL9541327 | 0.78 | NPC1 (0.42) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 | |
| SCHEMBL9584821 | 0.77 | LMNA (0.53) | NPC1RAB9APOLBL3MBTL1HPGD | |
| SCHEMBL9585067 | 0.77 | MAPT (0.43) | SLC1A3SLC1A2SLC1A1TRPM8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |