Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.55 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842932 | 0.90 | TP53 (0.66) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23054850 | 0.88 | EPHX2 (0.61) | EPHX2L3MBTL1 | |
| SCHEMBL8171576 | 0.86 | RORC (0.59) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7368975 | 0.86 | RORC (0.56) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24590188 | 0.85 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL19370084 | 0.85 | CNR1 (0.73) | ALDH1A1MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL16229451 | 0.85 | SIRT1 (0.64) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15480429 | 0.84 | HDAC1 (0.68) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL22298749 | 0.84 | KCNQ3 (0.59) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5541646 | 0.84 | EPHX2 (0.56) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751874-B | 1-Benzyl-4-ethylpiperazine derivatives as TRPV4-KCa2.3 coupling promoters and uses thereof | 江南大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-114751874-A | 1-benzyl-4-ethylpiperazine derivatives as TRPV4-KCa2.3 coupling promoting agents and application thereof | 江南大学 | 2022-07-15 | — | — | CN | disclosed |
| WO-1993013766-A1 | TREATMENT OF INVOLUNTARY MOVEMENTS WITH 5HT1A RECEPTOR AGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-07-22 | — | — | WO | disclosed |
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |