Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432409 | 0.81 | CASR (0.38) | KDM4EHPGDL3MBTL1NR1H4CYP2D6 | |
| SCHEMBL7444375 | 0.80 | TRPA1 (0.39) | KDM4EHPGDKMT2AMEN1LMNA | |
| SCHEMBL9134829 | 0.77 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTBLMPMP22 | |
| SCHEMBL9130921 | 0.77 | TSHR (0.47) | KDM4EKMT2AMEN1POLBTSHR | |
| SCHEMBL7435278 | 0.76 | ALDH1A1 (0.36) | KDM4ENR1H4KMT2AALDH1A1MEN1 | |
| SCHEMBL15658687 | 0.76 | NR4A1 (0.53) | KDM4EHPGDNR4A1NR4A2NR4A3 | |
| SCHEMBL7446494 | 0.75 | TRPA1 (0.43) | KDM4EHPGDKMT2AALDH1A1LMNA | |
| SCHEMBL7436705 | 0.74 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7354117 | 0.74 | KDM4E (0.48) | KDM4EHPGDL3MBTL1NR4A1NR4A2 | |
| SCHEMBL758421 | 0.74 | KDM4E (0.50) | KDM4EHPGDL3MBTL1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |