Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969927 | 0.70 | ACHE (0.54) | DRD4OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8969632 | 0.68 | ACHE (0.40) | DRD4OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8968484 | 0.68 | ACHE (0.54) | DRD4OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8968349 | 0.67 | ACHE (0.53) | DRD4MEN1KMT2A | |
| SCHEMBL8969711 | 0.59 | ACHE (0.43) | DRD4OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8969749 | 0.58 | ACHE (0.60) | OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8968969 | 0.58 | ACHE (0.49) | MEN1KMT2A | |
| SCHEMBL8969091 | 0.57 | ACHE (0.60) | DRD4OPRM1MEN1CYP2C9KMT2A | |
| SCHEMBL8969701 | 0.56 | ACHE (0.58) | DRD4MEN1KMT2A | |
| SCHEMBL4209029 | 0.55 | OPRM1 (0.58) | DRD4OPRM1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |