Sulfometuron

SCHEMBL9540465

Cc1cc(C)nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)n1.Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1.O=C(O)CCl

nearest known ligand 0.50

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.35

▸	CA12	O43570	4/20	0.34

▸	CA9	Q16790	4/20	0.34

▸	PCTP	Q9UKL6	1/20	0.34

▸	KDM4E	B2RXH2	1/20	0.33

▸	NPC1	O15118	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	ALOX15	P16050	1/20	0.33

▸	GAA	P10253	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfometuron SCHEMBL9551981	0.95	LMNA (0.36)	LMNACA12CA9PCTPKDM4E
Sulfometuron Methyl SCHEMBL9394949	0.88	GAA (0.38)	LMNACA9KDM4ENPC1MAPT
Sulfometuron Methyl SCHEMBL9755752	0.85	NPC1 (0.33)	KDM4ENPC1ALDH1A1MAPTALOX15
SCHEMBL4047513	0.83	GAA (0.43)	LMNAKDM4ENPC1ALDH1A1MAPT
SCHEMBL9394284	0.83	MAPT (0.36)	CA12CA9KDM4ENPC1ALDH1A1
Sulfometuron SCHEMBL29367129	0.78	LMNA (0.49)	LMNACA12CA9ALDH1A1MAPT
Sulfometuron SCHEMBL66180	0.78	LMNA (0.49)	LMNACA12CA9ALDH1A1MAPT
SCHEMBL8587808	0.74	GAA (0.37)	CA12CA9KDM4ENPC1ALDH1A1
SCHEMBL11072808	0.73	GAA (0.31)	ALOX15GAA
Sulfometuron Methyl SCHEMBL2438199	0.73	NPC1 (0.49)	LMNACA9KDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1993003020-A1	HERBICIDAL QUINOXALINYLOXY ETHERS	E.I. DU PONT DE NEMOURS AND COMPANY (US)	1993-02-18	—	—	WO	disclosed