Sulfometuron

Sulfometuron

SCHEMBL9551981

Cc1cc(C)nc(NC(=O)NS(=O)(=O)C2(C)C=CC=CC2C(=O)O)n1.Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.35
GAA P10253 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 1/20 0.33
PCTP Q9UKL6 1/20 0.33
CAMK2D Q13557 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfometuron SCHEMBL9540465 0.95 LMNA (0.35) LMNAALOX15GAACA12CA9
Sulfometuron Methyl SCHEMBL9394949 0.93 GAA (0.38) LMNAALOX15GAACA1CA2
Sulfometuron Methyl SCHEMBL9755752 0.89 NPC1 (0.33) ALOX15GAANPC1MAPTKDM4E
SCHEMBL4047513 0.87 GAA (0.43) LMNAALOX15GAANPC1RAB9A
SCHEMBL9394284 0.87 MAPT (0.36) GAACA1CA2MMP1MMP2
Sulfometuron SCHEMBL66180 0.82 LMNA (0.49) LMNAALOX15GAACA1CA2
Sulfometuron SCHEMBL29367129 0.82 LMNA (0.49) LMNAALOX15GAACA1CA2
SCHEMBL11072808 0.77 GAA (0.31) ALOX15GAA
Sulfometuron Methyl SCHEMBL2438199 0.76 NPC1 (0.49) LMNAGAACA1CA2MMP1
SCHEMBL11071268 0.76 GAA (0.30) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5189169-A Postemergence herbicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US disclosed