SCHEMBL9540472

SCHEMBL9540472

CC(=CC=C(c1ccc(Cl)cc1)C1CC1)c1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.34
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
TTR P02766 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
KCNQ3 O43525 1/20 0.32
KCNQ2 O43526 1/20 0.32
KCNE1 P15382 1/20 0.32
KCNQ1 P51787 1/20 0.32
PARP10 Q53GL7 1/20 0.32
PNLIP P16233 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9540468 1.00 LMNA (0.36) LMNAL3MBTL1SMN1; SMN2NPSR1LTB4R
SCHEMBL9540404 0.82 LMNA (0.36) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL9540399 0.82 LMNA (0.36) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL9643228 0.71 CXCL12 (0.34) PARP10
SCHEMBL9643233 0.71 CXCL12 (0.34) PARP10
SCHEMBL6230688 0.71 LMNA (0.34) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL6230685 0.71 LMNA (0.34) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL6932505 0.70 LMNA (0.35) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL6935659 0.70 LMNA (0.35) LMNAL3MBTL1SMN1; SMN2NPSR1CYP1A2
SCHEMBL10466636 0.70 FFAR4 (0.34) PARP10MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5223536-A Pyrethroid-like pesticides FMC CORPORATION (US) 1993-06-29 US disclosed
WO-1993001715-A1 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES FMC CORPORATION (US) 1993-02-04 WO disclosed