Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540399 | 1.00 | LMNA (0.36) | LMNAL3MBTL1NPSR1SMN1; SMN2PARP10 | |
| SCHEMBL9643228 | 0.89 | CXCL12 (0.34) | PARP10CXCL12PTGDR2 | |
| SCHEMBL9643233 | 0.89 | CXCL12 (0.34) | PARP10CXCL12PTGDR2 | |
| SCHEMBL10466635 | 0.88 | FFAR4 (0.34) | PARP10MGLL | |
| SCHEMBL10466636 | 0.88 | FFAR4 (0.34) | PARP10MGLL | |
| SCHEMBL9642455 | 0.84 | ALOX5 (0.40) | SMN1; SMN2MGLL | |
| SCHEMBL9642457 | 0.84 | ALOX5 (0.40) | SMN1; SMN2MGLL | |
| SCHEMBL9540468 | 0.82 | LMNA (0.36) | LMNAL3MBTL1NPSR1SMN1; SMN2PARP10 | |
| SCHEMBL9540472 | 0.82 | LMNA (0.36) | LMNAL3MBTL1NPSR1SMN1; SMN2PARP10 | |
| SCHEMBL6935659 | 0.80 | LMNA (0.35) | LMNAL3MBTL1NPSR1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223536-A | Pyrethroid-like pesticides | FMC CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| US-4975451-A | Insecticidal cyclopropyl di(aryl) 2-butenes | FMC CORPORATION (US) | 1990-12-04 | — | — | US | disclosed |