Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963034 | 0.95 | DRD2 (0.43) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8963069 | 0.92 | SLC18A3 (0.40) | DRD2SLC18A3HTR3ANPC1TP53 | |
| SCHEMBL8963076 | 0.92 | SLC18A3 (0.40) | DRD2SLC18A3HTR3ANPC1TP53 | |
| SCHEMBL8962818 | 0.87 | HTR3A (0.43) | DRD2SLC18A3HTR3ATP53TSHR | |
| SCHEMBL8962916 | 0.84 | HDAC2 (0.37) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8963054 | 0.83 | SLC18A3 (0.40) | DRD2SLC18A3HTR3ATP53TSHR | |
| SCHEMBL8963228 | 0.82 | P2RY14 (0.35) | CCR2NPC1RAB9AMAOBHDAC2 | |
| SCHEMBL8963237 | 0.82 | P2RY14 (0.35) | CCR2NPC1RAB9AMAOBHDAC2 | |
| SCHEMBL8963241 | 0.81 | ESR2 (0.41) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9300385 | 0.81 | ESR2 (0.41) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |