Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699545 | 0.83 | MAPT (0.52) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL9388019 | 0.81 | ALDH1A1 (0.46) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL9543716 | 0.79 | PKM (0.58) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL10055047 | 0.78 | MAPT (0.73) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL9698164 | 0.77 | MAPT (0.63) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7164868 | 0.75 | MAPT (0.84) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL102602 | 0.73 | MAPT (0.77) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL110446 | 0.73 | KAT2B (0.66) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL29390623 | 0.73 | KAT2B (0.66) | MAPTL3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL6198859 | 0.72 | KAT2B (0.80) | MAPTL3MBTL1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014088-A1 | ANTIHISTAMINIC PIPERAZINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |