Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387888 | 0.79 | PKM (0.61) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL9540982 | 0.79 | MAPT (0.52) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL8560755 | 0.79 | PKM (0.57) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL9387471 | 0.77 | CLK4 (0.38) | PKMMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL9690882 | 0.76 | MAPT (0.68) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL9685901 | 0.76 | PKM (0.57) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL31631301 | 0.75 | NPC1 (0.74) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL1738419 | 0.75 | NPC1 (0.74) | PKMNPC1MAPTRAB9ALMNA | |
| Methyl Alcohol SCHEMBL10640492 | 0.75 | NPC1 (0.70) | PKMNPC1MAPTRAB9ALMNA | |
| SCHEMBL9388019 | 0.74 | ALDH1A1 (0.46) | PKMMAPTRAB9ALMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014088-A1 | ANTIHISTAMINIC PIPERAZINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |