Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543951 | 0.80 | CFTR (0.32) | MTORALDH1A1HSD17B10MAPTTDP1 | |
| SCHEMBL9540048 | 0.80 | HPGD (0.34) | MTORALDH1A1HSD17B10MAPTTDP1 | |
| SCHEMBL23813891 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL3530679 | 0.77 | KEAP1 (0.50) | ALDH1A1HSD17B10MAPTTDP1 | |
| SCHEMBL5951820 | 0.77 | DGAT1 (0.40) | HDAC1HDAC6CYP1A2MAPTTDP1 | |
| SCHEMBL22598097 | 0.75 | GSK3B (0.41) | ALDH1A1MAPT | |
| SCHEMBL30884757 | 0.75 | GSK3B (0.41) | ALDH1A1MAPT | |
| SCHEMBL376859 | 0.72 | KDM4E (0.56) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL31473552 | 0.72 | GAA (0.46) | MTORHDAC1HDAC6CYP1A2 | |
| SCHEMBL9541212 | 0.70 | ALDH1A1 (0.33) | ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |